insulin like growth factor 1 (R&D Systems)
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insulin like growth factor 1
Insulin Like Growth Factor 1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 392 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+human+insulin+like+growth+factor+1/Recombinant+Human+IGF-I%2FIGF-1+Protein%2C+CF/bio_rxiv__64898__2026__01__13__699271-146-140-146
Average 96 stars, based on 392 article reviews
Insulin Like Growth Factor 1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 392 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+human+insulin+like+growth+factor+1/Recombinant+Human+IGF-I%2FIGF-1+Protein%2C+CF/bio_rxiv__64898__2026__01__13__699271-146-140-146
Average 96 stars, based on 392 article reviews
insulin like growth factor 1 - by Bioz Stars,
2026-10
96/100 stars
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Cell Culture:Article Title: Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis. Article Snippet: .. Briefly, the dissociated human embryoid bodies were plated onto growth factor–reduced Matrigel (33× dilution, thin coated; Corning Incorporated, Corning, NY, USA)– coated 24-well plates at a density of 2 × 105 cells per well and cultured in motor neuron medium (MNM) consisting of media hormone mix or KBM Neural Stem Cell medium (Kohjin Bio, Saitama, Japan) (75) supplemented with 2% B27 supplement (Thermo Fisher Scientific), 1% non-essential amino acids (NEAA), 50 nM retinoic acid (RA), 500 nM purmorphamine, 10 μM cyclic adenosine monophosphate (Sigma-Aldrich), recombinant brain-derived neurotrophic factor (10 ng/ml; R&D Systems, Minneapolis, MN, USA), recombinant glial cell line–derived neurotrophic factor (10 ng/ml; R&D Systems), Article Title: Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis Article Snippet: .. Briefly, the dissociated human embryoid bodies were plated onto growth factor–reduced Matrigel (33× dilution, thin coated; Corning Incorporated, Corning, NY, USA)–coated 24-well plates at a density of 2 × 10 5 cells per well and cultured in motor neuron medium (MNM) consisting of media hormone mix or KBM Neural Stem Cell medium (Kohjin Bio, Saitama, Japan) ( ) supplemented with 2% B27 supplement (Thermo Fisher Scientific), 1% non-essential amino acids (NEAA), 50 nM retinoic acid (RA), 500 nM purmorphamine, 10 μM cyclic adenosine monophosphate (Sigma-Aldrich), recombinant brain-derived neurotrophic factor (10 ng/ml; R&D Systems, Minneapolis, MN, USA), recombinant glial cell line–derived neurotrophic factor (10 ng/ml; R&D Systems), Recombinant:Article Title: Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis. Article Snippet: .. Briefly, the dissociated human embryoid bodies were plated onto growth factor–reduced Matrigel (33× dilution, thin coated; Corning Incorporated, Corning, NY, USA)– coated 24-well plates at a density of 2 × 105 cells per well and cultured in motor neuron medium (MNM) consisting of media hormone mix or KBM Neural Stem Cell medium (Kohjin Bio, Saitama, Japan) (75) supplemented with 2% B27 supplement (Thermo Fisher Scientific), 1% non-essential amino acids (NEAA), 50 nM retinoic acid (RA), 500 nM purmorphamine, 10 μM cyclic adenosine monophosphate (Sigma-Aldrich), recombinant brain-derived neurotrophic factor (10 ng/ml; R&D Systems, Minneapolis, MN, USA), recombinant glial cell line–derived neurotrophic factor (10 ng/ml; R&D Systems), Article Title: XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner Article Snippet: XPA overexpression lentivirus was purchased from Han Biotech (Hanbio, Shanghai, China) and the autophagy agonist rapamycin and autophagy inhibitor 3-MA were both purchased from MedChemExpress (MCE, NJ, USA). .. Article Title: Effects of grape phenolics, myricetin and piceatannol, on bovine granulosa and theca cell proliferation and steroid production in vitro. Article Snippet: Myricetin (a flavonol) and piceatannol (a stilbenoid) are naturally occurring phenolic compounds in red wine with cardio-protective and anti-carcinogenic effects, but their potential reproductive effects have not been investigated.. Thus, the present study was designed to determine if myricetin and piceatannol can directly affect ovarian function using bovine granulosa cells (GC) and theca cells (TC) as in vitro model systems to evaluate effects on cell proliferation and steroid production.. In Experiment 1 and 2, myricetin and piceatannol at 30 μM blocked insulin-like growth factor 1 (IGF1)-induced progesterone production by GC without affecting GC numbers. Article Title: Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells Article Snippet: .. The supplements included 2% vitamin B27, 1% N2 (Gibco, cat. 17,502–048), 10 ng/ml recombinant human brain-derived neurotrophic factor (BDNF) (R&D system, cat. 248-BD), 10 ng/ml recombinant human glial cell line-derived neurotrophic factor (GDNF) (R&D system, cat. 212-GD), 50 ng/ml small molecule recombinant human Sonic Hedgehog (hSHH) (R&D system, cat. 1845-SH), 200 ng/ml ascorbic acid (Wako chemicals, cat. 012–04802), 1 mM dibutyl cyclic AMP (Sigma–Aldrich, cat. D0627), 10 ng/ml Article Title: Insights Into Ferroptosis: Targeting Glycolysis to Treat Graves' Orbitopathy. Article Snippet: .. Reagents included erastin (Sigma-Aldrich, E7781), sodium selenite (Sigma-Aldrich, S5261; hereafter referred to as selenium), dichloroacetic acid (DCA; Sigma-Aldrich, D54702), IGF1R inhibitory antibody 1H7 (BD Biosciences, 555998; RRID: AB_396282), IGF1R inhibitory antibody teprotumumab (TMB; R&D Systems, MAB9718; RRID: AB_2892149), and Article Title: Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis Article Snippet: .. Briefly, the dissociated human embryoid bodies were plated onto growth factor–reduced Matrigel (33× dilution, thin coated; Corning Incorporated, Corning, NY, USA)–coated 24-well plates at a density of 2 × 10 5 cells per well and cultured in motor neuron medium (MNM) consisting of media hormone mix or KBM Neural Stem Cell medium (Kohjin Bio, Saitama, Japan) ( ) supplemented with 2% B27 supplement (Thermo Fisher Scientific), 1% non-essential amino acids (NEAA), 50 nM retinoic acid (RA), 500 nM purmorphamine, 10 μM cyclic adenosine monophosphate (Sigma-Aldrich), recombinant brain-derived neurotrophic factor (10 ng/ml; R&D Systems, Minneapolis, MN, USA), recombinant glial cell line–derived neurotrophic factor (10 ng/ml; R&D Systems), Article Title: Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells. Article Snippet: .. Hossain et al. Molecular Genetics and Metabolism Reports 31 (2022) 100852 vitamin B27, 1% N2 (Gibco, cat. 17,502–048), 10 ng/ml recombinant human brain-derived neurotrophic factor (BDNF) (R&D system, cat. 248-BD), 10 ng/ml recombinant human glial cell line-derived neurotrophic factor (GDNF) (R&D system, cat. 212-GD), 50 ng/ml small molecule recombinant human Sonic Hedgehog (hSHH) (R&D system, cat. 1845-SH), 200 ng/ml ascorbic acid (Wako chemicals, cat. 012–04802), 1 mM dibutyl cyclic AMP (Sigma–Aldrich, cat. D0627), 10 ng/ml Modification:Article Title: Effects of grape phenolics, myricetin and piceatannol, on bovine granulosa and theca cell proliferation and steroid production in vitro. Article Snippet: Myricetin (a flavonol) and piceatannol (a stilbenoid) are naturally occurring phenolic compounds in red wine with cardio-protective and anti-carcinogenic effects, but their potential reproductive effects have not been investigated.. Thus, the present study was designed to determine if myricetin and piceatannol can directly affect ovarian function using bovine granulosa cells (GC) and theca cells (TC) as in vitro model systems to evaluate effects on cell proliferation and steroid production.. In Experiment 1 and 2, myricetin and piceatannol at 30 μM blocked insulin-like growth factor 1 (IGF1)-induced progesterone production by GC without affecting GC numbers. Purification:Article Title: Effects of grape phenolics, myricetin and piceatannol, on bovine granulosa and theca cell proliferation and steroid production in vitro. Article Snippet: Myricetin (a flavonol) and piceatannol (a stilbenoid) are naturally occurring phenolic compounds in red wine with cardio-protective and anti-carcinogenic effects, but their potential reproductive effects have not been investigated.. Thus, the present study was designed to determine if myricetin and piceatannol can directly affect ovarian function using bovine granulosa cells (GC) and theca cells (TC) as in vitro model systems to evaluate effects on cell proliferation and steroid production.. In Experiment 1 and 2, myricetin and piceatannol at 30 μM blocked insulin-like growth factor 1 (IGF1)-induced progesterone production by GC without affecting GC numbers. Activity Assay:Article Title: Effects of grape phenolics, myricetin and piceatannol, on bovine granulosa and theca cell proliferation and steroid production in vitro. Article Snippet: Myricetin (a flavonol) and piceatannol (a stilbenoid) are naturally occurring phenolic compounds in red wine with cardio-protective and anti-carcinogenic effects, but their potential reproductive effects have not been investigated.. Thus, the present study was designed to determine if myricetin and piceatannol can directly affect ovarian function using bovine granulosa cells (GC) and theca cells (TC) as in vitro model systems to evaluate effects on cell proliferation and steroid production.. In Experiment 1 and 2, myricetin and piceatannol at 30 μM blocked insulin-like growth factor 1 (IGF1)-induced progesterone production by GC without affecting GC numbers. |